未读消息消息

店铺

我的订单收藏

拍卖

拍卖交易我的竞拍收藏

我的好友资金账户

客服 |

帮助中心 9:00-20:30 在线留言

客服电话

010-89648155

服务时间

客服咨询 8:00-21:00

纠纷处理 9:00-21:00

图书审核 9:00-18:00

监督与建议

请选择

手机孔网

BINARYDATAANALYSISOFRANDOMIZEDCLINICALTRIALSWITHNONCOMPLIANCE

BINARYDATAANALYSISOFRANDOMIZEDCLINICALTRIALSWITHNONCOMPLIANCE

分享

作者: Kung-Jong Lui 著

出版社: Wiley&Sons

出版时间: 2011-05

ISBN: 9780470660959

定价: 804.50

装帧: 精装

页数: 330页

正文语种: 英语

丛书: StatisticsinPractice

分类: 外文古旧书>英文书>医药卫生

It is quite common in a randomized clinical trial (RCT) to encounter patients who do not comply with their assigned treatment. Since noncompliance often occurs non-randomly, the commonly-used approaches, including both the as-treated (AT) and as-protocol (AP) analysis, and the intent-to-treat (ITT) (or as-randomized) analysis, are all well known to possibly produce a biased inference of the treatment efficacy. This book provides a systematic and organized approach to analyzing data for RCTs with noncompliance under the most frequently-encountered situations. These include parallel sampling, stratified sampling, cluster sampling, parallel sampling with subsequent missing outcomes, and a series of dependent Bernoulli sampling for repeated measurements. The author provides a comprehensive approach by using contingency tables to illustrate the latent probability structure of observed data. Using real-life examples, computer-simulated data and exercises in each chapter, the book illustrates the underlying theory in an accessible, and easy to understand way. Key features: Consort-flow diagrams and numerical examples are used to illustrate the bias of commonly used approaches, such as, AT analysis, AP analysis and ITT analysis for a RCT with noncompliance. Real-life examples are used throughout the book to explain the practical usefulness of test procedures and estimators. Each chapter is self-contained, allowing the book to be used as a reference source. Includes SAS programs which can be easily modified in calculating the required sample size. Biostatisticians, clinicians, researchers and data analysts working in pharmaceutical industries will benefit from this book. This text can also be used as supplemental material for a course focusing on clinical statistics or experimental trials in epidemiology, psychology and sociology.
内容简介:
It is quite common in a randomized clinical trial (RCT) to encounter patients who do not comply with their assigned treatment. Since noncompliance often occurs non-randomly, the commonly-used approaches, including both the as-treated (AT) and as-protocol (AP) analysis, and the intent-to-treat (ITT) (or as-randomized) analysis, are all well known to possibly produce a biased inference of the treatment efficacy. This book provides a systematic and organized approach to analyzing data for RCTs with noncompliance under the most frequently-encountered situations. These include parallel sampling, stratified sampling, cluster sampling, parallel sampling with subsequent missing outcomes, and a series of dependent Bernoulli sampling for repeated measurements. The author provides a comprehensive approach by using contingency tables to illustrate the latent probability structure of observed data. Using real-life examples, computer-simulated data and exercises in each chapter, the book illustrates the underlying theory in an accessible, and easy to understand way. Key features: Consort-flow diagrams and numerical examples are used to illustrate the bias of commonly used approaches, such as, AT analysis, AP analysis and ITT analysis for a RCT with noncompliance. Real-life examples are used throughout the book to explain the practical usefulness of test procedures and estimators. Each chapter is self-contained, allowing the book to be used as a reference source. Includes SAS programs which can be easily modified in calculating the required sample size. Biostatisticians, clinicians, researchers and data analysts working in pharmaceutical industries will benefit from this book. This text can also be used as supplemental material for a course focusing on clinical statistics or experimental trials in epidemiology, psychology and sociology.

查看详情

相关分类

Literature&Fiction文学与虚构 ScienceFiction&Fantasy科幻与玄幻 Romance浪漫小说 Mystery&Thrillers神秘与惊悚 Teens青少年读物 Biographies&Memoirs传记与自传 Comics&GraphicNovels动漫与绘画小说 ELT英语学习 Reference参考书 StandardTest标准考试 Business&Investing商业与投资 Self-Help励志自助

现货 Binary Data Analysis of Randomized Clinical Trials with Noncompliance (Statistics in Practice)[9780470660959]

九五品

环球外文图书专营店

上海市宝山区

平均发货46小时成功完成率92.83%

￥1238.00

券

100减20

立即购买加入购物车