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有机官能团Organic Functional Groups

有机官能团Organic Functional Groups

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作者: Thomas L Lemke 著

出版社: Oversea Publishing House

出版时间: 2003-09

ISBN: 9780781743815

定价: 419.00

装帧: 平装

开本: 16开

纸张: 胶版纸

页数: 156页

分类: 外文古旧书>英文书>医药卫生

Designed to be used as a self-paced review, this text outlines the functional groups common to organic chemistry, reviewing the general topics of nomenclature, physical and chemical properties, and metabolism. The text provides background material for the formal pharmacy courses in medicinal chemistry, easing the transition from general organic chemistry courses required of all pre-pharmacy students. The Fourth Edition will include a workbook on CD-ROM as well as an index on general drug metabolism. Students who use this text are able to complete difficult tasks such as: drawing a chemical structure or official chemical name; predicting solubility of chemicals in liquids; predicting and showing, with chemical structures, the metabolism of organic functional groups; predicting and showing instabilities, with chemical structures. Introduction

1 Water Solubility and Chemical Bonding

　Van der Waals Attraction(Forces)

　Dipole—Dipole Bonding(Hyd rogen Bond)

　Ionic Attraction

　Ion-Dipole Bonding

2 Alkanes(CnH2n+2)

3 Alkenes(CnH2 n)

　Cycloalkanes：Alkene Isomers

4 Aromatic Hydrocarbons

5 Halogenated Hydrocarbons

6 Alcohols

7 Phenols

8 Ethers

9 Aldehydes and Ketones

10 Amines

　Quaternary Ammonium Salts

11 Carboxylic Acids

12 Functional Derivatives of Carboxylic Acids

　Esters

　Amides

　Carbonates，Carbamates，and Ureas

　Amidines and Guanidines

13 Sulfonic Acids and Sulfonamides

　Sulfonic Acids

　Sulfonamides

14 Thioethers and Nitro Groups

　Thioethers

　Nitro Groups

15 Heterocycles

　Th ree—Membered Ring Heterocydes

　Four-Membered Ring Heterocycles

　Five．Membered Ring Heterocycles

　Five—Membered Ring Heterocycles With Two or More Heteroatoms

　Six—Membered Ring Heterocycles

　Six．Membered Ring Heterocycles With Two Heteroatoms

　Saturated Six—Membered Heterocycles

　Seven-—And Eight--Membered Ring Heterocycles

　Bicyclic Heterocycles：Five—Membered Ring Plus Six．Membered Ring

　Bicyclic Heterocycles：Six-Membered Ring Plus

　Six—Membered Ring

　Bicyclic Heterocycles：Six—Membered Ring Plus Seven-Membered Ring

　Tricyclic Heterocycles

16 0Ugonucleotides and N ucleic Acids

17 Proteins

18 Predicting Water Solubility

　Empi ric Method

　Analytic Method

A Stereoisomerism--Asymmetric Motecules

B Acidity and Basicity

　Definitions of Acids and Bases

　Relative Strengths of Acids and Bases

　Reaction of an Acid W；t}1 a Base in Water

　Acidic and Basic Organic Function Groups

C Drug Metabolism

　Oxygenase Enzymes

　Hydrolase Enzymes

　Conjugation Reactions

　Index
内容简介:
Designed to be used as a self-paced review, this text outlines the functional groups common to organic chemistry, reviewing the general topics of nomenclature, physical and chemical properties, and metabolism. The text provides background material for the formal pharmacy courses in medicinal chemistry, easing the transition from general organic chemistry courses required of all pre-pharmacy students. The Fourth Edition will include a workbook on CD-ROM as well as an index on general drug metabolism. Students who use this text are able to complete difficult tasks such as: drawing a chemical structure or official chemical name; predicting solubility of chemicals in liquids; predicting and showing, with chemical structures, the metabolism of organic functional groups; predicting and showing instabilities, with chemical structures.
目录:
Introduction

1 Water Solubility and Chemical Bonding

　Van der Waals Attraction(Forces)

　Dipole—Dipole Bonding(Hyd rogen Bond)

　Ionic Attraction

　Ion-Dipole Bonding

2 Alkanes(CnH2n+2)

3 Alkenes(CnH2 n)

　Cycloalkanes：Alkene Isomers

4 Aromatic Hydrocarbons

5 Halogenated Hydrocarbons

6 Alcohols

7 Phenols

8 Ethers

9 Aldehydes and Ketones

10 Amines

　Quaternary Ammonium Salts

11 Carboxylic Acids

12 Functional Derivatives of Carboxylic Acids

　Esters

　Amides

　Carbonates，Carbamates，and Ureas

　Amidines and Guanidines

13 Sulfonic Acids and Sulfonamides

　Sulfonic Acids

　Sulfonamides

14 Thioethers and Nitro Groups

　Thioethers

　Nitro Groups

15 Heterocycles

　Th ree—Membered Ring Heterocydes

　Four-Membered Ring Heterocycles

　Five．Membered Ring Heterocycles

　Five—Membered Ring Heterocycles With Two or More Heteroatoms

　Six—Membered Ring Heterocycles

　Six．Membered Ring Heterocycles With Two Heteroatoms

　Saturated Six—Membered Heterocycles

　Seven-—And Eight--Membered Ring Heterocycles

　Bicyclic Heterocycles：Five—Membered Ring Plus Six．Membered Ring

　Bicyclic Heterocycles：Six-Membered Ring Plus

　Six—Membered Ring

　Bicyclic Heterocycles：Six—Membered Ring Plus Seven-Membered Ring

　Tricyclic Heterocycles

16 0Ugonucleotides and N ucleic Acids

17 Proteins

18 Predicting Water Solubility

　Empi ric Method

　Analytic Method

A Stereoisomerism--Asymmetric Motecules

B Acidity and Basicity

　Definitions of Acids and Bases

　Relative Strengths of Acids and Bases

　Reaction of an Acid W；t}1 a Base in Water

　Acidic and Basic Organic Function Groups

C Drug Metabolism

　Oxygenase Enzymes

　Hydrolase Enzymes

　Conjugation Reactions

　Index

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